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- ProSci
- 美国
- PSI-60-856-400ul
- 2025年07月15日
- WB
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
This Mouse Irf3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-72 amino acids from the N-terminal region of mouse Irf3.
- 保存条件：
Store at 4℃ for three months and -20℃, stable for up to one year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
WB
- 抗体英文名：
Mouse Irf3 Antibody
- 抗体名：
Mouse Irf3 Antibody
- 规格：
400ul
Mouse Irf3 抗体，Mouse Irf3 Antibody，Mouse Irf3 抗体,Mouse Irf3 Antibody
产品名称：Mouse Irf3 抗体-Mouse Irf3 Antibody
产品货号：PSI-60-856-400ul
产品规格：400ul
背景资料：Mediates interferon-stimulated response element (ISRE) promoter activation. Functions as a molecular switch for antiviral activity. DsRNA generated during the course of an viral infection leads to IRF3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of genes under the control of ISRE. The complex binds to the IE and PRDIII regions on the IFN-alpha and IFN-beta promoters respectively. IRF-3 does not have any transcription activation domains (By similarity).
保存建议：Mouse Irf3 抗体-Mouse Irf3 AntibodyStore at 4℃ for three months and -20℃, stable for up to one year
应用类型：WB
点击：Mouse Irf3 抗体-Mouse Irf3 Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验Isotype-specific immunostaining with mouse primary antibodies on mouse tissue
) Briefly, substitute your anti H+L pan-reactive secondary antibody with an anti-isotype heavy chain specific secondary. Be aware of possible odd crossreactivties (e.g. many goat anti mouse IgG 1 heavy chain do stain rat IgG 2a
Euthanasia Euthanasia and mouse necropsies require prior IACUC approval. The mode of euthanasia should be chosen which minimizes pain or distress
Immunostaining of Mouse Atherosclerotic Lesions
and regulators in lesions. The principle of the technique is that an antibody is incubated with the tissue under conditions that favor a specific interaction with its antigen. This is subsequently visualized most commonly by a chromogenic substrate that produces
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