Mouse Irf3 抗体-Mouse Irf3 Antib

Mouse Irf3 抗体，Mouse Irf3 Antibody，Mouse Irf3 抗体,Mouse Irf3 Antibody

产品名称：Mouse Irf3 抗体-Mouse Irf3 Antibody

产品货号：PSI-60-856-400ul

产品规格：400ul

背景资料：Mediates interferon-stimulated response element (ISRE) promoter activation. Functions as a molecular switch for antiviral activity. DsRNA generated during the course of an viral infection leads to IRF3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of genes under the control of ISRE. The complex binds to the IE and PRDIII regions on the IFN-alpha and IFN-beta promoters respectively. IRF-3 does not have any transcription activation domains (By similarity).

保存建议：Mouse Irf3 抗体-Mouse Irf3 AntibodyStore at 4℃ for three months and -20℃, stable for up to one year

应用类型：WB

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