NFKBp65 抗体 -NFKBp65 Antibody

NFKBp65 抗体 ，NFKBp65 Antibody ，NFKBp65 抗体 ,NFKBp65 Antibody

产品名称：NFKBp65 抗体 -NFKBp65 Antibody

产品货号：PSI-59-721-400ul

产品规格：400ul

背景资料：NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL(MIM 164910), RELA, or RELB (MIM 604758) to form the NFKB complex.The p50 (NFKB1)/p65 (RELA) heterodimer is the most abundant form ofNFKB. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA,MIM 164008 or NFKBIB, MIM 604495), which inactivate NFKB bytrapping it in the cytoplasm. Phosphorylation of serine residues onthe I-kappa-B proteins by kinases (IKBKA, MIM 600664, or IKBKB, MIM603258) marks them for destruction via the ubiquitination pathway,thereby allowing activation of the NFKB complex. Activated NFKBcomplex translocates into the nucleus and binds DNA atkappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or Gpurine; and Y is a C or T pyrimidine).

保存建议：NFKBp65 抗体 -NFKBp65 Antibody Store at 4℃ for three months and -20℃, stable for up to one year

应用类型：WB, IF

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