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- ProSci
- 美国
- PSI-57-400-400ul
- 2025年07月12日
- WB
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
This C4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 655-684 amino acids from the Central region of human C4B.
- 保存条件：
Store at 4℃ for three months and -20℃, stable for up to one year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
WB
- 抗体英文名：
C4B Antibody
- 抗体名：
C4B Antibody
- 规格：
400ul
C4B 抗体，C4B Antibody，C4B 抗体,C4B Antibody
产品名称：C4B 抗体-C4B Antibody
产品货号：PSI-57-400-400ul
产品规格：400ul
背景资料：This gene encodes the basic form of complement factor 4,part of the classical activation pathway. The protein is expressedas a single chain precursor which is proteolytically cleaved into atrimer of alpha, beta, and gamma chains prior to secretion. Thetrimer provides a surface for interaction between theantigen-antibody complex and other complement components. The alphachain may be cleaved to release C4 anaphylatoxin, a mediator oflocal inflammation. Deficiency of this protein is associated withsystemic lupus erythematosus. This gene localizes to the majorhistocompatibility complex (MHC) class III region on chromosome 6.Varying haplotypes of this gene cluster exist, such thatindividuals may have 1, 2, or 3 copies of this gene. In addition,this gene exists as a long form and a short form due to thepresence or absence of a 6.4 kb endogenous HERV-K retrovirus inintron 9.
保存建议：C4B 抗体-C4B AntibodyStore at 4℃ for three months and -20℃, stable for up to one year
应用类型：WB
点击：C4B 抗体-C4B Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验补体成分 C4(C4a/C4b) 补体成分：C4 血清浓度(μg/ml)：200～500 分子量(kDa)：210 亚单位(链)及分子量(kDa)：α：90β：78γ：33 激活产物：C4a；C4b 生物学活性：C4a 弱的过敏毒素作用 C4b 组成CP中的C3、C5转化
Purification and Functional Characterization of C4b-Binding Protein (C4BP)
C4b-binding protein (C4BP) is a soluble, 570 kDa large glycoprotein, present in plasma at a concentration of approximately 200 mg/L. C4BP is the main inhibitor of the classical and lectin pathways of complement, where it controls C4b-mediated
Evaluation of Complement-Dependent Cytotoxicity Using ATP Measurement and C1q/C4b Binding
method to evaluate the binding of C1q on the Fc region and the binding of C4b on cell surface. The luminescence method coupled with complement protein analysis by flow cytometry encompasses all needed methods to evaluate antibody ability to trigger CDC.
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