Neutrophil elastase 抗体-Neutrop

Neutrophil elastase 抗体，Neutrophil elastase Antibody，Neutrophil elastase 抗体,Neutrophil elastase Antibody

产品名称：Neutrophil elastase 抗体-Neutrophil elastase Antibody

产品货号：PSI-56-220-400ul

产品规格：400ul

背景资料：Elastases form a subfamily of serine proteases thathydrolyze many proteins in addition to elastin. Humans have sixelastase genes which encode the structurally similar proteins. Theproduct of this gene hydrolyzes proteins within specializedneutrophil lysosomes, called azurophil granules, as well asproteins of the extracellular matrix following the protein'srelease from activated neutrophils. The enzyme may play a role indegenerative and inflammatory diseases by its proteolysis ofcollagen-IV and elastin of the extracellular matrix. This proteindegrades the outer membrane protein A (OmpA) of E. coli as well asthe virulence factors of such bacteria as Shigella, Salmonella andYersinia. Mutations in this gene are associated with cyclicneutropenia and severe congenital neutropenia (SCN). This gene isclustered with other serine protease gene family members,azurocidin 1 and proteinase 3 genes, at chromosome 19pter. All 3genes are expressed coordinately and their protein products arepackaged together into azurophil granules during neutrophildifferentiation.

保存建议：Neutrophil elastase 抗体-Neutrophil elastase AntibodyStore at 4℃ for three months and -20℃, stable for up to one year

应用类型：WB

点击：Neutrophil elastase 抗体-Neutrophil elastase Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。