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- ProSci
- 美国
- PSI-50-221-0.1mL
- 2025年07月13日
- WB
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser133 of rat CREB.
- 保存条件：
stored at -20℃ and is stable at -20℃ for at least 1 year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
WB
- 抗体英文名：
CREB (phospho Ser133) Antibody
- 抗体名：
CREB (phospho Ser133) Antibody
- 规格：
0.1mL
CREB (phospho Ser133) 抗体，CREB (phospho Ser133) Antibody，CREB (phospho Ser133) 抗体,CREB (phospho Ser133) Antibody
产品名称：CREB (phospho Ser133) 抗体-CREB (phospho Ser133) Antibody
产品货号：PSI-50-221-0.1mL
产品规格：0.1mL
背景资料：It is well known that the control of gene expression involves activation of protein kinase cascades that regulate transcription factors within the nucleus (Karin and Hunter, 1995). The cyclic AMP response element binding protein (CREB) is one of the best characterized stimulus-induced transcription factors (Montminy, 1997). This transcription factor is a component of intracellular signaling events that regulate a wide range of biological functions, from spermatogenesis to circadian rhythms and memory (Shaywitz and Greenberg, 1999; Silva et al., 1998). A variety of protein kinases including protein kinase A (PKA), mitogenactivated protein kinases (MAPKs), and Ca2+/calmodulin-dependent protein kinases (CaMKs) phosphorylate CREB at serine 133 (Ser133), and phosphorylation of Ser133 are required for CREB-mediated transcription (Johannessen et al., 2004; Kornhauser et al., 2002).
保存建议：CREB (phospho Ser133) 抗体-CREB (phospho Ser133) Antibody stored at -20℃ and is stable at -20℃ for at least 1 year
应用类型：WB
点击：CREB (phospho Ser133) 抗体-CREB (phospho Ser133) Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验【求助】于NF-KB 激活，P65磷酸化位点是ser536还是ser276?
伽利略 ............................... chenlydd 两者都有,蛋白磷酸化水平与其功能密切相关：检测其磷酸化水平可用抗磷酸化位点抗体检测。www.cellsignal.com公司有相应抗体出售。 P65磷酸化位点: regulates apoptosis: S536‑p regulates cell growth: S536‑p regulates cell
antibody. For antiphosphoCREB (IgG, 0.7 mg/ml), I use 1:5,000 - 1:20,000 dilution in 4% BSA in TBST. This should be titrated for optimal results. I incubate with primary Ab 3 hours - overnight at room temp with shaking.10. Remove the antibody solution
Using Phospho‐Motif Antibodies to Determine Kinase Substrates
comprising both the phosphorylated residue and the surrounding residues that determine kinase specificity, with degenerate residues taking up the remaining positions. Currently, several categories of phospho?motif antibody are commercially available
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