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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
mGluR 1a polyclonal antibody was raised against a peptide from the C-terminal region of mGluR1a.
- 保存条件:
stored at -20℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB, IHC
- 抗体英文名:
Metabotropic Glutamate Receptor 1a Antibody
- 抗体名:
Metabotropic Glutamate Receptor 1a Antibody
- 规格:
0.1mL
Metabotropic Glutamate Receptor 1a 抗体,Metabotropic Glutamate Receptor 1a Antibody,Metabotropic Glutamate Receptor 1a 抗体,Metabotropic Glutamate Receptor 1a Antibody
产品名称:Metabotropic Glutamate Receptor 1a 抗体-Metabotropic Glutamate Receptor 1a Antibody
产品货号:PSI-50-101-0.1mL
产品规格:0.1mL
背景资料:The metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. In contrast activation of Group II metabotropic receptors (mGluR2 and mGluR3) leads to inhibition of adenylate cyclase.
保存建议:Metabotropic Glutamate Receptor 1a 抗体-Metabotropic Glutamate Receptor 1a Antibody stored at -20℃
应用类型:WB, IHC
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文献和实验Functional Study of Glutamate Receptor Channels in Brain Slices
Glutamate is the major excitatory neurotransmitter in the central nervous system (CNS). Glutamate binds to and activates receptors coupled to both ligand-gated ion channels (ionotropic) and G proteins (metabotropic
Receptor Knock-Out and Knock-In Strategies
-out of the receptor. This is called the third generation knock-out. In the following sections, we introduce examples of the materials and methods based on our in vivo analyses of the metabotropic glutamate receptor-subtype 1 (mGluR1).
Isolation of Receptor Clones by Expression Screening in Xenopus Oocytes
, a metabotropic glutamate receptor (mGluR) clone was also identified with the oocyte system (5 ).
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