TIMP-1 抗体-TIMP-1 Antibody

TIMP-1 抗体，TIMP-1 Antibody，TIMP-1 抗体,TIMP-1 Antibody

产品名称：TIMP-1 抗体-TIMP-1 Antibody

产品货号：PSI-38-215-0.1mg

产品规格：0.1mg

背景资料：Tissue inhibitor of metalloproteinases 1 (TIMP1) and Tissue inhibitor of metalloproteinases 2 (TIMP 2) have similar properties, specifically in inhibiting enzymes of the matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP1 forms a complex of 1:1 stoichiometry with activated interstitial collagenases, activated stromelysin, active form of 72kDa Type IV collagenase (also known as MMP2 or gelatinase A), and latent and active forms of 92kDa Type IV collagenase (also known as MMP0 or gelatinase B). TIMPs inhibit the proteolytic invasiveness of tumour cells and normal placental trophoblast cells. TIMP1 is produced in low (pg/mL) levels by most cell types. Treatment of cells with the phorbol ester TPA stimulates production of TIMP1 in some cell types, but the low protein levels produced often require concentration of cell culture media to visualize the bands by Western Blotting.

保存建议：TIMP-1 抗体-TIMP-1 AntibodyTIMP-1 antibody is stable for at least 2 years from date of receipt at -20℃

应用类型：E, WB, Neut

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