- ￥22
- ProSci
- 美国
- PSI-38-155-0.05mg
- 2025年07月15日
- E, WB
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hIGF-BP7. Human IGF-BP7 specific antibody was purified by affinity chromatography and then biotinylated.
- 保存条件：
IGF-BP7 antibody is stable for at least 2 years from date of receipt at -20℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
E, WB
- 抗体英文名：
IGF-BP7 Antibody (biotin)
- 抗体名：
IGF-BP7 Antibody (biotin)
- 规格：
0.05mg
IGF-BP7 抗体 (biotin)，IGF-BP7 Antibody (biotin)，IGF-BP7 抗体 (biotin),IGF-BP7 Antibody (biotin)
产品名称：IGF-BP7 抗体 (biotin)-IGF-BP7 Antibody (biotin)
产品货号：PSI-38-155-0.05mg
产品规格：0.05mg
背景资料：IGF-BPs form high affinity complexes with both IGF-I and IGF-II and act to control of the distribution, function and activity of IGFs in various cell tissues and body fluids. There are seven named IGF-BPs. IGF-BP7 plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle, and increased apoptosis. IGF-BP7 is expressed in a wide range of normal human tissues and it usually shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin.
保存建议：IGF-BP7 抗体 (biotin)-IGF-BP7 Antibody (biotin)IGF-BP7 antibody is stable for at least 2 years from date of receipt at -20℃
应用类型：E, WB
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文献和实验The Avidin-Biotin Complex (ABC) Method and Other Avidin-Biotin Binding Methods
These methods involve, at their core, the vitamin biotin and the protein avidin, which bind together irreversibly. By establishing a biotin link, through avidin, between the horseradish peroxidase enzyme and a secondary antibody reagent
The Avidin-Biotin Complex(ABC) Method
, between the horseradish peroxidase enzyme and a secondary antibody reagent, enzyme localization can be achieved at the site of primary antibody interaction with the specimen (see ) Fig. 1 ). The biotin molecule is small and can be easily conjugated to immunoglobulin
Identification of Deacetylase Substrates with the Biotin Switch Approach
The identification of lysine-acetylated proteins and deacetylase substrates has primarily relied on protein immune-affinity techniques with antibodies that recognize acetylated lysine residues (Kac antibodies). While these antibody-based
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