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- ProSci
- 美国
- PSI-38-104-0.05mg
- 2025年07月12日
- E, WB
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hNanog. Human Nanog specific antibody was purified by affinity chromatography and then biotinylated.
- 保存条件：
Nanog antibody is stable for at least 2 years from date of receipt at -20℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
E, WB
- 抗体英文名：
Nanog Antibody (biotin)
- 抗体名：
Nanog Antibody (biotin)
- 规格：
0.05mg
Nanog 抗体 (biotin)，Nanog Antibody (biotin)，Nanog 抗体 (biotin),Nanog Antibody (biotin)
产品名称：Nanog 抗体 (biotin)-Nanog Antibody (biotin)
产品货号：PSI-38-104-0.05mg
产品规格：0.05mg
背景资料：Nanog is a newly identified homeodomain-bearing transcriptional factor. Nanog expression is specific to early embryos and pluripotential stem cells including mouse and human embryonic stem (ES) and embryonic germ (EG) cells. It is a key molecule involved in the signaling pathway for maintaining the capacity for self-renewal and pluripotency, bypassing regulation by the STAT3 pathway. Nanog mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells. Nanog-deficient ES cells lose pluripotency and differentiate into extraembryonic endoderm lineage. Thus it is one of the molecular markers suitable for recognizing the undifferentiated state of stem cells in the mouse and human.
保存建议：Nanog 抗体 (biotin)-Nanog Antibody (biotin)Nanog antibody is stable for at least 2 years from date of receipt at -20℃
应用类型：E, WB
点击：Nanog 抗体 (biotin)-Nanog Antibody (biotin)查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验The Avidin-Biotin Complex (ABC) Method and Other Avidin-Biotin Binding Methods
These methods involve, at their core, the vitamin biotin and the protein avidin, which bind together irreversibly. By establishing a biotin link, through avidin, between the horseradish peroxidase enzyme and a secondary antibody reagent
The Avidin-Biotin Complex(ABC) Method
, between the horseradish peroxidase enzyme and a secondary antibody reagent, enzyme localization can be achieved at the site of primary antibody interaction with the specimen (see ) Fig. 1 ). The biotin molecule is small and can be easily conjugated to immunoglobulin
Identification of Deacetylase Substrates with the Biotin Switch Approach
The identification of lysine-acetylated proteins and deacetylase substrates has primarily relied on protein immune-affinity techniques with antibodies that recognize acetylated lysine residues (Kac antibodies). While these antibody-based
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