Lipoma Preferred Partner 抗体-Li

Lipoma Preferred Partner 抗体，Lipoma Preferred Partner Antibody，Lipoma Preferred Partner 抗体,Lipoma Preferred Partner Antibody

产品名称：Lipoma Preferred Partner 抗体-Lipoma Preferred Partner Antibody

产品货号：PSI-36-343-50ug

产品规格：50ug

背景资料：Lipoma preferred partner (LPP) is encoded by the preferred fusion partner gene of the high mobility group protein HMGI-C. LPP is frequently affected by chromosomal translocations in a major group of soft tissue lipomas, as well as in a parosteal lipoma and in pulmonary chondroid hamartomas. The resulting fusion proteins comprise three DNA binding domains of HMGI-C fused to two or three C-terminal LIM domains of LPP and a reciprocal product, respectively. Expression of a HMGI-C/LPP fusion protein causes malignant transformation of fibroblasts. Similar to its relatives zyxin and TRIP (thyroid receptor interacting protein 6) / ZRP-1 (zyxin-related protein 1), LPP consists of a N-terminal proline-rich domain followed by three C-terminal LIM domains (double zinc finger structures that are involved in protein-protein interactions). Like the cytoskeletal protein zyxin, LPP localizes to focal adhesions and cell-cell adherens junctions. LPP harbors a nuclear export signal and displays transcriptional activation capacity.

保存建议：Lipoma Preferred Partner 抗体-Lipoma Preferred Partner AntibodyStable for at least 1 year after receipt when stored at -20℃

应用类型：ICC, IP, WB

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