GPx8 抗体-GPx8 Antibody

GPx8 抗体，GPx8 Antibody，GPx8 抗体,GPx8 Antibody

产品名称：GPx8 抗体-GPx8 Antibody

产品货号：PSI-36-337-100ug

产品规格：100ug

背景资料：GPxs are glutathione peroxidases involved in balancing the H2O2 homeostasis in signaling cascades. GPxs have been known to catalyze the reduction of H2O2 or organic hydroperoxides to water or the corresponding alcohols, respectively, typically using glutathione (GSH) as reductant. GPx8 (probable glutathione peroxidase 8) is a 209-aa, 24kDa protein with an N-terminal cytosolic tip, a predicted transmembrane segment and a catalytic domain located in the endoplasmic reticulum (ER) lumen. GPx8 is a CysGPxs with low glutathione peroxidase activity. A recent study identified GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease. GPx8 cleavage by NS3-4A occurs at Cys11, removing the cytosolic tip of GPx8 and was observed in different experimental systems as well as in liver biopsies from patients with chronic hepatitis C.

保存建议：GPx8 抗体-GPx8 AntibodyStable for at least 1 year after receipt when stored at -20℃

应用类型：ICC, WB

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