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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant mouse Bmf.
- 保存条件:
Stable for at least 1 year after receipt when stored at -20℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
大鼠
- 应用范围:
Flow, IP, WB
- 抗体英文名:
Bmf Antibody [9G10]
- 抗体名:
Bmf Antibody [9G10]
- 规格:
100ug
Bmf 抗体 [9G10],Bmf Antibody [9G10],Bmf 抗体 [9G10],Bmf Antibody [9G10]
产品名称:Bmf 抗体 [9G10]-Bmf Antibody [9G10]
产品货号:PSI-36-173-100ug
产品规格:100ug
背景资料:Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis.
保存建议:Bmf 抗体 [9G10]-Bmf Antibody [9G10]Stable for at least 1 year after receipt when stored at -20℃
应用类型:Flow, IP, WB
点击:Bmf 抗体 [9G10]-Bmf Antibody [9G10]查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验作用。 (三)BH3-Only亚族 这一亚族成员仅含有一个BH同源结构域,即BH3结构域,包括Bid、Bad和Bim等。BH3-only蛋白本身在无Bax或Bak的情况下不能引起细胞凋亡,因此可能通过为Bax/Bak传递凋亡信号而发挥作用。细胞中的BH3-only蛋白的活动空间是被严格限制的,如Bim和Bmf通过动力蛋白轻链(dyneinlightchain,DLC)分别固定在微管和肌动蛋白骨架上。基因敲除实验显示,BH3-only蛋白在不同组织器官中发挥作用,如Bid调节Fas抗体引起的肝细胞
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