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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant human Fas.
- 保存条件:
Stable for at least 1 year after receipt when stored at -20℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
Flow, FUNC, IP, WB
- 抗体英文名:
Fas Antibody [APO-1-3] (preservative free)
- 抗体名:
Fas Antibody [APO-1-3] (preservative free)
- 规格:
50ug
Fas 抗体 [APO-1-3] (preservative free),Fas Antibody [APO-1-3] (preservative free),Fas 抗体 [APO-1-3] (preservative free),Fas Antibody [APO-1-3] (preservative free)
产品名称:Fas 抗体 [APO-1-3] (preservative free)-Fas Antibody [APO-1-3] (preservative free)
产品货号:PSI-36-167-50ug
产品规格:50ug
背景资料:Fas (CD95) is a member of the death receptor (DR) family, a subfamily of the tumor necrosis factor receptor superfamily. The formation of the Fas death-inducing signaling complex (DISC) is the initial step of Fas signaling. Activation of procaspase-8 at the DISC leads to the induction of DR-mediated apoptosis. Stimulation of Fas has been also reported to trigger non-apoptotic pathways. It has been shown that membrane-bound FasL is essential for the cytotoxic activity, whereas soluble FasL appears to promote autoimmunity and tumorigenesis via induction of non-apoptotic pathways, in particular NF-kappaB.
保存建议:Fas 抗体 [APO-1-3] (preservative free)-Fas Antibody [APO-1-3] (preservative free)Stable for at least 1 year after receipt when stored at -20℃
应用类型:Flow, FUNC, IP, WB
点击:Fas 抗体 [APO-1-3] (preservative free)-Fas Antibody [APO-1-3] (preservative free)查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验Electroporation is a method for introducing DNA into cells by using a high-voltage electric field. This method is very simple and easily manipulated. We describe here a method for the modification of tumor cells with the Fas/Apo-1 (CD95) antigen
/Western blotting assays. Another factor important in achieving optimal results is the degree of sensitivity of cells to the antibody-induced apoptosis. As an example, CD95 (Fas)-induced apoptosis of human Jurkat cell line by monoclonal antibody EOS
Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
. Whereas interest in the apoptosis-inducing molecules TNF and Fas ligand has peaked because of their participation in events such as autoimmune disorders, activation-induced cell death, immune privilege, and tumor evasion from the immune system, another death-inducing family member
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