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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Human CD5 recombinant protein was used as the immunogen for this anti-CD5 antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
Flow, IF, IHC
- 抗体英文名:
CD5 Antibody [SPM546]
- 抗体名:
CD5 Antibody [SPM546]
- 规格:
100ug
CD5 抗体 [SPM546],CD5 Antibody [SPM546],CD5 抗体 [SPM546],CD5 Antibody [SPM546]
产品名称:CD5 抗体 [SPM546]-CD5 Antibody [SPM546]
产品货号:PSI-34-187-100ug
产品规格:100ug
背景资料:Recognizes a 67kDa transmembrane protein which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
保存建议:CD5 抗体 [SPM546]-CD5 Antibody [SPM546]Aliquot and Store at 2-8℃
应用类型:Flow, IF, IHC
点击:CD5 抗体 [SPM546]-CD5 Antibody [SPM546]查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验CD5 分子 CD5 常用单克隆抗体或代号:T1,UCHT2,T101,Leul 主要表达细胞:T,Thy,BsubC T细胞 分子质量(kDa)和结构:gp67(清除剂受体) 功 能:与CD72结合,T细胞信号转导和增殖,CD5+ B细胞与自身免疫有关 CD5 Belongs to ancient scavenger receptor family
药物递送:抗体偶联脂质纳米颗粒 (Ab-LNP) — 体内 CAR-T 的前沿策略
指导性植入支架的混合策略;⑤ 以及 Cas9 包装的包膜递送载体 (Cas9-EDV) 和病毒模拟融合纳米囊泡 (FuNV)[3]。 图 3. 体内 CAR-T 疗法递送平台[3]。 a. LNP 或聚合物通过与 T 细胞抗原 (如 CD3、CD4、CD5 和 CD8) 的相互作用,被抗体或抗体片段功能化以选择性地结合 T 细胞。mRNA 然后在细胞质中的核糖体上被翻译,导致 CAR 分子的表达,从而暂时生成
;7:711[6] 杨希峰,沈德诚,金宇光等. HI47,一种人成熟B细胞单克隆抗体制备,鉴定及其生物特性研究。上海免疫学杂志,1990;10(2):65-68[7] McLaughlin P,Grillo-Lopez AJ, Link BK,et al. Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma:half of patient respond to a four-dose
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