Tyrosinase 抗体 [SPM360]-Tyrosin

Tyrosinase 抗体 [SPM360]，Tyrosinase Antibody [SPM360]，Tyrosinase 抗体 [SPM360],Tyrosinase Antibody [SPM360]

产品名称：Tyrosinase 抗体 [SPM360]-Tyrosinase Antibody [SPM360]

产品货号：PSI-34-177-100ug

产品规格：100ug

背景资料：Recognizes a cluster of proteins between 70-80kDa, identified as tyrosinase. Occasionally a minor band at 55kDa is also detected. This mAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this mAb shows tyrosinase in melanotic as well as amelanotic variants. This mAb is a useful marker for melanocytes and melanomas.

保存建议：Tyrosinase 抗体 [SPM360]-Tyrosinase Antibody [SPM360]Aliquot and Store at 2-8℃

应用类型：Flow, IF, IHC

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