p53 抗体 [SPM590]-p53 Antibody [

p53 抗体 [SPM590]，p53 Antibody [SPM590]，p53 抗体 [SPM590],p53 Antibody [SPM590]

产品名称：p53 抗体 [SPM590]-p53 Antibody [SPM590]

产品货号：PSI-34-174-100ug

产品规格：100ug

背景资料：Recognizes a 53kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.

保存建议：p53 抗体 [SPM590]-p53 Antibody [SPM590]Aliquot and Store at 2-8℃

应用类型：Flow, IF, WB, IHC

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