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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant human protein was used as the immunogen for the VCAM-1 antibody.
- 保存条件:
Aliquot and Store at 2-8℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
小鼠
- 应用范围:
Flow, IF, IHC-P
- 抗体英文名:
VCAM-1 Antibody [CDLA106]
- 抗体名:
VCAM-1 Antibody [CDLA106]
- 规格:
100ug
VCAM-1 抗体 [CDLA106],VCAM-1 Antibody [CDLA106],VCAM-1 抗体 [CDLA106],VCAM-1 Antibody [CDLA106]
产品名称:VCAM-1 抗体 [CDLA106]-VCAM-1 Antibody [CDLA106]
产品货号:PSI-33-994-100ug
产品规格:100ug
背景资料:Vascular cell adhesion molecule-1 (VCAM-1), also called L1CAM and CD106, is important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation. [UniProt]
保存建议:VCAM-1 抗体 [CDLA106]-VCAM-1 Antibody [CDLA106]Aliquot and Store at 2-8℃
应用类型:Flow, IF, IHC-P
点击:VCAM-1 抗体 [CDLA106]-VCAM-1 Antibody [CDLA106]查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验Nature 综述导读:FDA 批准第 100 个抗体药物!抗体药物的研究方向在哪里?
批准了第 50 种抗体,距离第一个抗体已经过去了 29 年。2021 年 4 月,随着葛兰素史克 PD1 阻断剂 dostarlimab 的批准,抗体药物仅用了 6 年多的时间就达到了 100 个,进入了「百抗」新时代(图五)。 图五 Nature Reviews Drug Discovery 20, 10 (2021) 上面提到的 100 个抗体并不是单纯经典的单克隆的裸抗体(naked antibody),其中也包括了抗体片段已经工程化修饰抗体的各种偶联形式。其中包括有抗体药物偶联(ADC
A Method to Isolate and Purify Human Bone Marrow Stromal Stem Cells
the rare STRO-1bright expressing fraction that contains all of the colony-forming BMSSC, based on their co-expression of a secondary cell surface marker, CD106 (VCAM-1).
A Method to Isolate, Purify, and Characterize Human Periodontal Ligament Stem Cells
on the expression of MSC-associated surface markers STRO-1 antigen, CD146 (MUC-18), CD29 (integrin β-1), CD44, and CD106 (VCAM-1). Although no single antibody demonstrates specificity for MSCs, isolation based on the expression of individual markers results
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