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- ProSci
- 美国
- PSI-33-784-100ug
- 2025年07月14日
- WB, IP, IHC-P
- 小鼠
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- 文献和实验
- 技术资料
- 免疫原：
A human recombinant partial protein was used as the immunogen for this Retinoblastoma antibody.
- 保存条件：
Aliquot and Store at 2-8℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
小鼠
- 应用范围：
WB, IP, IHC-P
- 抗体英文名：
Retinoblastoma / Rb Antibody [SPM353]
- 抗体名：
Retinoblastoma / Rb Antibody [SPM353]
- 规格：
100ug
Retinoblastoma / Rb 抗体 [SPM353]，Retinoblastoma / Rb Antibody [SPM353]，Retinoblastoma / Rb 抗体 [SPM353],Retinoblastoma / Rb Antibody [SPM353]
产品名称：Retinoblastoma / Rb 抗体 [SPM353]-Retinoblastoma / Rb Antibody [SPM353]
产品货号：PSI-33-784-100ug
产品规格：100ug
背景资料：Recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.
保存建议：Retinoblastoma / Rb 抗体 [SPM353]-Retinoblastoma / Rb Antibody [SPM353]Aliquot and Store at 2-8℃
应用类型：WB, IP, IHC-P
点击：Retinoblastoma / Rb 抗体 [SPM353]-Retinoblastoma / Rb Antibody [SPM353]查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验Analysis of E7/Rb Associations
of fundamental events, such as cell proliferation and apoptosis. The best-characterized activity of E7 from HPV type 16, the most frequently detected type in cervical cancer, is its ability to bind and induce degradation of the tumor-suppressor retinoblastoma
Analysis of RB Action in DNA Damage Checkpoint Response
. The retinoblastoma tumor suppressor (RB) is a critical effector of DNA damage checkpoint function by eliciting G1-phase cell cycle arrest following genotoxic stress. Here, we describe methodologies for evaluation of three facets of RB action in the DNA damage
Abrogation of the RB-p16Tumor Suppressor Pathway in Human Lung Cancer
of this late G1 restriction point is the protein product of the retinoblastoma gene, pRB (1). In its hypophosphorylated form, pRB binds E2F-family transcription factors. Functional inactivation of pRB leads to release of these transcription factors
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