MUC-1 抗体 [HMPV]-MUC-1 Antibody

MUC-1 抗体 [HMPV]，MUC-1 Antibody [HMPV]，MUC-1 抗体 [HMPV],MUC-1 Antibody [HMPV]

产品名称：MUC-1 抗体 [HMPV]-MUC-1 Antibody [HMPV]

产品货号：PSI-33-443-100ug

产品规格：100ug

背景资料：This mAb recognizes full-length MUC1/Mucin-1/Epithelial Marker Antigen/EMA in a glycosylation-independent manner and can bind to the fully glycosylated protein. The dominant epitope of this mAb is APDTR in the VNTR region. It reacts with the core peptide of the MUC1 protein, which is a member of a family of mucin glycoproteins that are characterized by high carbohydrate content, O-linked oligosaccharides, high molecular weight (>200kDa) and an amino acid composition rich in serine, threonine, proline and glycine. The core protein contains a domain of 20 amino-acid tandem repeats that functions as multiple epitopes for the mAb. Incomplete glycosylation of some tumor-associated mucins may lead to variable unmasking of the multiple peptide epitopes leading to the observed differences in staining intensity between normal and malignant tissues. This mAb reacts with both normal and malignant epithelia of various tissues including breast and colon.

保存建议：MUC-1 抗体 [HMPV]-MUC-1 Antibody [HMPV]Aliquot and Store at 2-8℃

应用类型：WB, Flow, IF, IHC-P

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