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- ProSci
- 美国
- PSI-33-510-100ug
- 2025年07月13日
- WB, Flow, IF
- 小鼠
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant human protein was used as the immunogen for the LAMP3 antibody.
- 保存条件：
Aliquot and Store at 2-8℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
小鼠
- 应用范围：
WB, Flow, IF
- 抗体英文名：
LAMP3 Antibody [LAMP3/529]
- 抗体名：
LAMP3 Antibody [LAMP3/529]
- 规格：
100ug
LAMP3 抗体 [LAMP3/529]，LAMP3 Antibody [LAMP3/529]，LAMP3 抗体 [LAMP3/529],LAMP3 Antibody [LAMP3/529]
产品名称：LAMP3 抗体 [LAMP3/529]-LAMP3 Antibody [LAMP3/529]
产品货号：PSI-33-510-100ug
产品规格：100ug
背景资料：This mAb recognizes protein of 26kDa-60kDa, which is identified as CD63/LAMP3. Its epitope is different from that of mAb LAMP3/803 or LAMP3/968 or NKI/C3 or MX-49.129.5. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63/LAMP3 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. It is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63/LAMP3 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. Deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.
保存建议：LAMP3 抗体 [LAMP3/529]-LAMP3 Antibody [LAMP3/529]Aliquot and Store at 2-8℃
应用类型：WB, Flow, IF
点击：LAMP3 抗体 [LAMP3/529]-LAMP3 Antibody [LAMP3/529]查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验, 2001，28(3): 415 [３８] 王京兰, 万晶宏, 罗凌，等. 蛋白质组研究中肽质量指纹谱鉴定方法的建立及应用. 生物化学与生物物理学报, 2000，32: 373-378 [３９] Guo X, Ying W, Wan J, et al. Proteomic characterization of early stage differentiation of mouse embryonic stem cells into neural cells induced
1. 引言 自我复制，忠实地拷贝自身的基因组，这是所有生命的一个确定的特性。在当今的生命体中，这个最基本的生命活动由不同种类的多核苷酸聚合酶来实现 [1] 。除了基因组的扩增外，多核苷酸聚合酶还有一系列核心的生物功能，包括转录、DNA 修复以及端粒维持。近年来，人们发现某些特殊的聚合酶参与很多不同的生命活动，包括从适应突变、抗体亲和力成熟到抵抗紫外线引起的 DNA 损伤 [2]，而且，还有可能参与 RNA 干扰。异常的聚合酶功能可引起癌症的发生 [4]，许多聚合酶，尤其是病毒的聚合
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