Beta-2 Microglobulin 抗体 [B2M/9

Beta-2 Microglobulin 抗体 [B2M/961]，Beta-2 Microglobulin Antibody [B2M/961]，Beta-2 Microglobulin 抗体 [B2M/961],Beta-2 Microglobulin Antibody [B2M/961]

产品名称：Beta-2 Microglobulin 抗体 [B2M/961]-Beta-2 Microglobulin Antibody [B2M/961]

产品货号：PSI-33-458-100ug

产品规格：100ug

背景资料：Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes.

保存建议：Beta-2 Microglobulin 抗体 [B2M/961]-Beta-2 Microglobulin Antibody [B2M/961]Aliquot and Store at 2-8℃

应用类型：Flow, IF, IHC-P

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