RET 抗体 [6E4C4] -RET Antibody [

RET 抗体 [6E4C4] ，RET Antibody [6E4C4] ，RET 抗体 [6E4C4] ,RET Antibody [6E4C4]

产品名称：RET 抗体 [6E4C4] -RET Antibody [6E4C4]

产品货号：PSI-32-211-0.1mL

产品规格：0.1mL

背景资料：RET (ret proto-oncogene) is a member of the cadherin superfamily and a receptor tyrosine kinase, which are cell-surface molecules that transduce signals for cell growth and differentiation. It can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Ligands that bind the Ret receptor include the glial cell line-derived neurotropic factor (GDNF) and its congeners neurturin, persephin and artemin. Alterations in the corresponding Ret gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma and a congenital developmental disorder known as Hirschsprung抯 disease. The Tyr905 residue located in the Ret kinase domain plays a crucial role in Ret catalytic and biological activity. Substitution of Phe for Tyr905 dramatically inhibits Ret autophosphorylation activity.

保存建议：RET 抗体 [6E4C4] -RET Antibody [6E4C4] stored at -20℃, stable for one year

应用类型：E, WB

点击：RET 抗体 [6E4C4] -RET Antibody [6E4C4] 查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。