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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CPSF4.
- 保存条件:
For short periods of storage (days) store at 4℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB
- 抗体英文名:
CPSF4 Antibody
- 抗体名:
CPSF4 Antibody
- 规格:
100ul
CPSF4 抗体,CPSF4 Antibody,CPSF4 抗体,CPSF4 Antibody
产品名称:CPSF4 抗体-CPSF4 Antibody
产品货号:PSI-29-389-100ul
产品规格:100ul
背景资料:Inhibition of the nuclear export of poly (A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs.
保存建议:CPSF4 抗体-CPSF4 AntibodyFor short periods of storage (days) store at 4℃
应用类型:E, WB
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