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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SMAD4.
- 保存条件:
For short periods of storage (days) store at 4℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB
- 抗体英文名:
SMAD4 Antibody
- 抗体名:
SMAD4 Antibody
- 规格:
100ul
SMAD4 抗体,SMAD4 Antibody,SMAD4 抗体,SMAD4 Antibody
产品名称:SMAD4 抗体-SMAD4 Antibody
产品货号:PSI-27-474-100ul
产品规格:100ul
背景资料:SMAD4 is one of the Smad family members, which are essential intracellular signalling components of the transforming growth factor-beta (TGF-beta) superfamily. Smad2 and Smad3 are structurally highly similar and mediate TGF-beta signals. Smad4 is distantly related to Smads 2 and 3, and forms a heteromeric complex with Smad2 after TGF-beta or activin stimulation. TGF-beta induces heteromeric complexes of Smads 2, 3 and 4, and their concomitant translocation to the nucleus, which is required for efficient TGF-beta signal transduction
保存建议:SMAD4 抗体-SMAD4 AntibodyFor short periods of storage (days) store at 4℃
应用类型:E, WB
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文献和实验dingding2004 想找一个药物来阻断SMAD4 的作用。不知有没有做过的。 SMAD4 是在转录水平发挥作用的,如果有这种药物,加在要干预的细胞培养液中,可以发挥作用吗? dingding2004 自己顶下啊 caoying207 唉,没想到2年以后,我也在找SMAD4阻断剂(抑制剂 ),前辈,你找到了吗? skyzhuz 半
Molecular Detection of Smad2/Smad4 Alterations in Colorectal Tumors
The signaling pathways mediated by the transforming growth factor-β (TGF-β) family of factors are implicated in a wide array of biological processes including cell differentiation and proliferation, determination of cell fate during embryogenesis
Direct Sequencing for Juvenile Polyposis Gene SMAD4/DPC4 Mutations
Juvenile polyposis (JP) is a rare dominantly inherited tumor predisposition syndrome, the typical lesion being a benign hamartomatous intestinal polyp with dilated crypts. Solitary juvenile polyps are relatively common in childhood, and appear
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