CAPN10 抗体-CAPN10 Antibody

CAPN10 抗体，CAPN10 Antibody，CAPN10 抗体,CAPN10 Antibody

产品名称：CAPN10 抗体-CAPN10 Antibody

产品货号：PSI-26-646-100ul

产品规格：100ul

背景资料：CAPN10 is the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM) and located within the NIDDM1 region. Multiple alternative transcript variants encoding different isoforms have been described for this gene.

保存建议：CAPN10 抗体-CAPN10 AntibodyFor short periods of storage (days) store at 4℃

应用类型：E, WB

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