NSD1 抗体-NSD1 Antibody

NSD1 抗体，NSD1 Antibody，NSD1 抗体,NSD1 Antibody

产品名称：NSD1 抗体-NSD1 Antibody

产品货号：PSI-24-011-50uL

产品规格：50uL

背景资料：This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene.

保存建议：NSD1 抗体-NSD1 AntibodyStore at -20℃

应用类型：WB

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