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- ProSci
- 美国
- PSI-18-337-50uL
- 2025年07月10日
- WB,IF
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human DNA polymerase eta (NP_006493.1).
- 保存条件：
Store at -20℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
WB,IF
- 抗体英文名：
DNA polymerase eta Antibody
- 抗体名：
DNA polymerase eta Antibody
- 规格：
50uL
DNA polymerase eta 抗体，DNA polymerase eta Antibody，DNA polymerase eta 抗体,DNA polymerase eta Antibody
产品名称：DNA polymerase eta 抗体-DNA polymerase eta Antibody
产品货号：PSI-18-337-50uL
产品规格：50uL
背景资料：This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.
保存建议：DNA polymerase eta 抗体-DNA polymerase eta AntibodyStore at -20℃
应用类型：WB,IF
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文献和实验We report a simple homogeneous fluorescence assay for quantification of DNA polymerase function in high throughput. The fluorescence signal is generated by the DNA polymerase triggering opening of a molecular beacon extension of the template
The Polymerase Chain Reaction (PCR)
. Did He Really Invent PCR? • The basic principle of replicating a piece of DNA using two primers had already been described by Gobind Khorana in 1971:– Kleppe et al. (1971) J. Mol. Biol. 56, 341-346. • Progress was limited by primer synthesis and polymerase
能催化从四种5′-脱氧核苷三磷酸游离出焦磷酸而使DNA进行聚合反应的酶。EC2.7.7.7.。必须以DNA为模板，合成的DNA与模板具有互补的碱基排列（碱基互补性）。是与DNA复制和修复有关的重要的酶，虽可从许多组织分离出来，但对大肠杆菌的这种酶的研究较为先进。康伯格（A.Kornberg，1958）最初从大肠杆菌将此酶纯化，并弄清了其结构和特异性，但以后经过分子遗传学的研究，已明确了这种酶主要与DNA修复有关。因此重新进行与DNA复制有关酶的检索，发现两种新的酶。康伯格最初发现的酶称为
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