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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide of human NFKB2
- 保存条件:
Store at -20℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB
- 抗体英文名:
NFKB2 Antibody, KO Validated
- 抗体名:
NFKB2 Antibody, KO Validated
- 规格:
50uL
NFKB2 抗体, KO Validated,NFKB2 Antibody, KO Validated,NFKB2 抗体, KO Validated,NFKB2 Antibody, KO Validated
产品名称:NFKB2 抗体, KO Validated-NFKB2 Antibody, KO Validated
产品货号:PSI-18-227-50uL
产品规格:50uL
背景资料:This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.
保存建议:NFKB2 抗体, KO Validated-NFKB2 Antibody, KO ValidatedStore at -20℃
应用类型:WB
点击:NFKB2 抗体, KO Validated-NFKB2 Antibody, KO Validated查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验Methods 2016 年的文章2,国际抗体验证工作小组(International Working Group on Antibody Validation, IWGAV)提出 5 种支柱策略(conceptual pillar),如下:1. 基因策略(敲除验证):利用 CRISPR/Cas 或 RNAi 等技术对靶基因进行敲除(knock out)或敲低(knock down),分别检测对照组与 KO 组的信号。2. 正交策略:在多种样品中使用一种与抗体无关的定量方法,然后比较分析基于抗体的定量
双特异抗体(Bispecific antibody)的简介和制作方法
、双特异抗体简介双特异抗体(Bispecific antibody)是含有两个不同配体结合位点的免疫球蛋白分子。自然状态下不存在双特异性抗体,只能通过特殊方法进行制备。以往双特异抗体的制备方法有化学交联法,杂合F(ab')2 分子法和鼠杂交瘤法等。化学交联法生产双特异抗体的异源性,批与批之间的不稳定性,以及抗体特异性易受某些修饰或不当连接而改变的特性,使得该法生产的双特异抗体不适于体内使用。以巯基交联蛋白酶消化片断F(ab')生产的双特异杂交分子,成分虽较均一,但费时费力,且产量很低。杂交瘤法生产
Improving Phage Display Throughput by Using Hyperphage, Miniaturized Titration and pVIII (g8p) ELISA
Hyperphage is a substitute for M13KO7 helper phage used in antibody phage display. It allows to improve the antibody display efficiency on phage by 2-3 orders of magnitude. This is achieved by forcing the packaging E. coli cell to exclusively
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