IDH1 抗体, KO Validated-IDH1 Ant

IDH1 抗体, KO Validated，IDH1 Antibody, KO Validated，IDH1 抗体, KO Validated,IDH1 Antibody, KO Validated

产品名称：IDH1 抗体, KO Validated-IDH1 Antibody, KO Validated

产品货号：PSI-18-211-50uL

产品规格：50uL

背景资料：Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. It contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

保存建议：IDH1 抗体, KO Validated-IDH1 Antibody, KO ValidatedStore at -20℃

应用类型：WB,IP

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