Myelin Basic protein 抗体-Myelin

Myelin Basic protein 抗体，Myelin Basic protein Antibody，Myelin Basic protein 抗体,Myelin Basic protein Antibody

产品名称：Myelin Basic protein 抗体-Myelin Basic protein Antibody

产品货号：PSI-16-692-50uL

产品规格：50uL

背景资料：The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes.

保存建议：Myelin Basic protein 抗体-Myelin Basic protein AntibodyStore at -20℃

应用类型：WB,IHC

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