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- ProSci
- 美国
- PSI-16-534-50uL
- 2025年07月10日
- WB,IF
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human IDE (NP_004960.2).
- 保存条件：
Store at -20℃
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
WB,IF
- 抗体英文名：
IDE Antibody, KO Validated
- 抗体名：
IDE Antibody, KO Validated
- 规格：
50uL
IDE 抗体, KO Validated，IDE Antibody, KO Validated，IDE 抗体, KO Validated,IDE Antibody, KO Validated
产品名称：IDE 抗体, KO Validated-IDE Antibody, KO Validated
产品货号：PSI-16-534-50uL
产品规格：50uL
背景资料：This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.
保存建议：IDE 抗体, KO Validated-IDE Antibody, KO ValidatedStore at -20℃
应用类型：WB,IF
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文献和实验
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