DiMethyl-UHRF1-K385 pAb-DiMeth

DiMethyl-UHRF1-K385 pAb，DiMethyl-UHRF1-K385 pAb，DiMethyl-UHRF1-K385 pAb,DiMethyl-UHRF1-K385 pAb

产品名称：DiMethyl-UHRF1-K385 pAb-DiMethyl-UHRF1-K385 pAb

产品货号：PSI-16-372-50uL

产品规格：50uL

背景资料：This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12.

保存建议：DiMethyl-UHRF1-K385 pAb-DiMethyl-UHRF1-K385 pAbStore at -20℃

应用类型：IHC,IF

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