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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-211 of human TNFR1 (NP_001056.1).
- 保存条件:
Store at -20℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB,IHC
- 抗体英文名:
TNFR1 Antibody
- 抗体名:
TNFR1 Antibody
- 规格:
50uL
TNFR1 抗体,TNFR1 Antibody,TNFR1 抗体,TNFR1 Antibody
产品名称:TNFR1 抗体-TNFR1 Antibody
产品货号:PSI-16-031-50uL
产品规格:50uL
背景资料:This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients.
保存建议:TNFR1 抗体-TNFR1 AntibodyStore at -20℃
应用类型:WB,IHC
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文献和实验TRAF‐Mediated TNFR‐Family Signaling
Keywords: TNF family; TNFR family; IL?1R/TLR; TRAF proteins; signal transduction; inflammation GO TO THE FULL PROTOCOL: PDF or HTML at Wiley Online Library
Genetic Engineering in the Mouse: Tuning TNF/TNFR Expression
With the exponential increase in the number of genes identified by various genome projects, it has become imperative that efficient methods be developed for deciphering gene function. Genetically engineered strains of mice are now critical
在免疫反应方面,基于抗原的刺激在体内形成、并与抗原作特异性结合的蛋白质之总称。其化学实质是免疫球蛋白。抗体,按照抗原抗体反应的类型可分别称为沉淀素、凝集素、溶血素、溶菌素、抗毒素、中和抗体等,但这些并不等于有相应的不同抗体存在,一般多只表明抗体反应的多样性而已。抗体在血清中含量最多(体液抗体=humoral antibody);含有某特定抗体的血清称为抗血或免疫血清。
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