PDHA1 抗体-PDHA1 Antibody

PDHA1 抗体，PDHA1 Antibody，PDHA1 抗体,PDHA1 Antibody

产品名称：PDHA1 抗体-PDHA1 Antibody

产品货号：PSI-15-043-50uL

产品规格：50uL

背景资料：The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

保存建议：PDHA1 抗体-PDHA1 AntibodyStore at -20℃

应用类型：IHC,IF

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