p38 MAPK 抗体-p38 MAPK Antibody

p38 MAPK 抗体，p38 MAPK Antibody，p38 MAPK 抗体,p38 MAPK Antibody

产品名称：p38 MAPK 抗体-p38 MAPK Antibody

产品货号：PSI-13-989-50uL

产品规格：50uL

背景资料：The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

保存建议：p38 MAPK 抗体-p38 MAPK AntibodyStore at -20℃

应用类型：WB

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