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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant fusion protein containing a sequence corresponding to amino acids 350-590 of human DMPK (NP_004400.4).
- 保存条件:
Store at -20℃
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
WB
- 抗体英文名:
DMPK Antibody
- 抗体名:
DMPK Antibody
- 规格:
50uL
DMPK 抗体,DMPK Antibody,DMPK 抗体,DMPK Antibody
产品名称:DMPK 抗体-DMPK Antibody
产品货号:PSI-13-652-50uL
产品规格:50uL
背景资料:The protein encoded by this gene is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases. Substrates for this enzyme include myogenin, the beta-subunit of the L-type calcium channels, and phospholemman. The 3' untranslated region of this gene contains 5-38 copies of a CTG trinucleotide repeat. Expansion of this unstable motif to 50-5,000 copies causes myotonic dystrophy type I, which increases in severity with increasing repeat element copy number. Repeat expansion is associated with condensation of local chromatin structure that disrupts the expression of genes in this region. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
保存建议:DMPK 抗体-DMPK AntibodyStore at -20℃
应用类型:WB
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文献和实验
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