DUSP6 抗体-DUSP6 Antibody

DUSP6 抗体，DUSP6 Antibody，DUSP6 抗体,DUSP6 Antibody

产品名称：DUSP6 抗体-DUSP6 Antibody

产品货号：PSI-13-231-100uL

产品规格：100uL

背景资料：The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene.

保存建议：DUSP6 抗体-DUSP6 AntibodyStore at 4℃

应用类型：WB,IF

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