DCX 抗体-DCX Antibody

DCX 抗体，DCX Antibody，DCX 抗体,DCX Antibody

产品名称：DCX 抗体-DCX Antibody

产品货号：PSI-13-054-100uL

产品规格：100uL

背景资料：This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.

保存建议：DCX 抗体-DCX AntibodyStore at 4℃

应用类型：WB,IHC

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