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- ProSci
- 美国
- PSI-8085-0.02mg
- 2025年07月11日
- E, WB, IHC-P
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
JAK2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human JAK2.<br>The immunogen is located within the last 50 amino acids of JAK2.
- 保存条件：
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
E, WB, IHC-P
- 抗体英文名：
JAK2 Antibody
- 抗体名：
JAK2 Antibody
- 规格：
0.02mg
JAK2 抗体，JAK2 Antibody，JAK2 抗体,JAK2 Antibody
产品名称：JAK2 抗体-JAK2 Antibody
产品货号：PSI-8085-0.02mg
产品规格：0.02mg
背景资料：JAK2 is a member of the JAK family of kinases that also include JAK1, JAK3, and TYK2 (1,2). JAK kinases are activated following tyrosine phosphorylation of cytokine receptors after ligand binding. JAK2 activation promotes the recruitment and phosphorylation of STAT3 and STAT5. These transcription factors then translocate to the nucleus where they bind specific DNA promoter sequences resulting in the transcription of genes that regulate cell proliferation, differentiation, and apoptosis (3). Mice with a disrupted JAK2 gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis (4).
保存建议：JAK2 抗体-JAK2 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型：E, WB, IHC-P
点击：JAK2 抗体-JAK2 Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验Recently, a point mutation in the JAK2 gene, JAK2 V617F , was discovered in several myeloid proliferative neoplasms including polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). Demonstration
Methods for Detecting Mutations in the Human JAK2 Gene
Mutations in the JAK2 gene are prevalent in the human myeloid malignancies, being present in virtually all cases of polycythemia vera, and a significant proportion of patients with other myeloproliferative disorders. Various methods
人JAK2 酶联免疫分析（ ELISA ） 试剂盒使用说明书 本试剂仅供研究使用 目的：本试剂盒用于测定人血清，血浆及相关液体样本中JAK2 的 含量。 实验原理： 本试剂盒应用双抗体夹心法测定标本中 人 JAK2 水平。用纯化的 人 JAK2 抗体 包被微孔板，制成固相抗体，往包被单抗的微孔中依次加入 JAK2 ，再与 HRP 标记的 JAK2 抗体结合，形成抗体 - 抗原 - 酶标抗体复合物，经过彻底洗涤后加底物
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