SREBF1 抗体-SREBF1 Antibody

SREBF1 抗体，SREBF1 Antibody，SREBF1 抗体,SREBF1 Antibody

产品名称：SREBF1 抗体-SREBF1 Antibody

产品货号：PSI-7853-0.02mg

产品规格：0.02mg

背景资料：The sterol regulatory element binding transcription factor 1 (SREBF1) is a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis (1). The related protein SREBF2 also binds SRE1 and activates transcription in an additive fashion to SREBF1 (2). SREBF1 is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1 (3). The SREBF1 proteins are important in the regulation of genes involved in lipid metabolism, while SREBF2 has been more closely associated with cholesterol synthesis and accumulation (4).

保存建议：SREBF1 抗体-SREBF1 Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, IHC-P, IF

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