DEPTOR 抗体-DEPTOR Antibody

DEPTOR 抗体，DEPTOR Antibody，DEPTOR 抗体,DEPTOR Antibody

产品名称：DEPTOR 抗体-DEPTOR Antibody

产品货号：PSI-7787-0.02mg

产品规格：0.02mg

背景资料：DEPTOR is an mTOR (mammalian target of rapamycin)-interacting protein whose expression is negatively regualted by mTOR complex 1 (mTORC1) and mTORC2 (1). Loss of DEPTOR activates RP6SK1, Akt1, and SGK1, promotes cell growth and survival, and activates mTORC1 and mTORC2 kinase activities. DEPTOR expression is low in most cancers, but is often elevated in multiple myelomas (1). In respons to stimulation by mitogens, DEPTOR is rapidly phosphorylated leading to its ubiquitination and degradation, allowing mTOR to generate an auto-amplification loop to promotes its own full activation (2).

保存建议：DEPTOR 抗体-DEPTOR Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, IHC-P

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