Beclin 2 抗体-Beclin 2 Antibody

Beclin 2 抗体，Beclin 2 Antibody，Beclin 2 抗体,Beclin 2 Antibody

产品名称：Beclin 2 抗体-Beclin 2 Antibody

产品货号：PSI-7989-0.02mg

产品规格：0.02mg

背景资料：Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells (1,2). Beclin 2 is a mammalian specific homolog of the autophagy protein Beclin 1 (3). Like Beclin 1, Beclin 2 interacts with Bcl-2 and class III PI3K complex components. However, Beclin 2 functions in an additional lysosomal degradation pathway and is required for ligand-induced endolysosomal degradation of several G protein-coupled receptors (3). Beclin 2 is also required for agonist-induced lysosome-mediated degradation of EGFR in lung cancer cells, suggesting that it may also play a role in regulating other intracellular signaling pathways (4).

保存建议：Beclin 2 抗体-Beclin 2 Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, IHC-P, IF

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