IL-37 抗体 -IL-37 Antibody

IL-37 抗体 ，IL-37 Antibody ，IL-37 抗体 ,IL-37 Antibody

产品名称：IL-37 抗体 -IL-37 Antibody

产品货号：PSI-7499-0.02mg

产品规格：0.02mg

背景资料：Interleukin 37 (IL-37) is a member of the interleukin 1 cytokine family (reviewed in 1). It can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). IL-37 also binds to interleukin 18 binding protein (IL18BP), an inhibitory binding protein of interleukin 18 (IL18), and subsequently forms a complex with IL18 receptor beta subunit, and through which it inhibits the activity of IL18 (1). IL-37 can also interact with Smad3 and expression of IL-37 in macrophages or epithelial cells resulted in near complete suppression of pro-inflammatory cytokines, suggesting that IL-37 may act as a natural suppressor of the innate inflammatory and immune responses (2,3).

保存建议：IL-37 抗体 -IL-37 Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, IHC-P, IF

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