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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KPNA6 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of human KPNA6.<br>The immunogen is located within amino acids 70 - 120 of KPNA6.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB, IF
- 抗体英文名:
KPNA6 Antibody
- 抗体名:
KPNA6 Antibody
- 规格:
0.02mg
KPNA6 抗体,KPNA6 Antibody,KPNA6 抗体,KPNA6 Antibody
产品名称:KPNA6 抗体-KPNA6 Antibody
产品货号:PSI-5991-0.02mg
产品规格:0.02mg
背景资料:KPNA6 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA6 belongs to a subfamily within the KPNA family that also includes IPOA5&6. Down-regulation of KPNA6 by RNAi expression in HeLa cells strongly inhibited cell proliferation, possibly due to blocking the nuclear import of specific factors essential for cell growth and proliferation. KPNA6 also interacts with the Rev protein of HIV-1 and promote its nuclear import.
保存建议:KPNA6 抗体-KPNA6 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB, IF
点击:KPNA6 抗体-KPNA6 Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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