- ￥22
- ProSci
- 美国
- PSI-5627-0.02mg
- 2025年07月13日
- E, WB, IHC-P, IF
- 兔
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
BCAS2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human BCAS2.<br>The immunogen is located within the last 50 amino acids of BCAS2.
- 保存条件：
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期：
1年
- 级别：
科研级别
- 库存：
100
- 供应商：
艾美捷科技
- 宿主：
兔
- 应用范围：
E, WB, IHC-P, IF
- 抗体英文名：
BCAS2 Antibody
- 抗体名：
BCAS2 Antibody
- 规格：
0.02mg
BCAS2 抗体，BCAS2 Antibody，BCAS2 抗体,BCAS2 Antibody
产品名称：BCAS2 抗体-BCAS2 Antibody
产品货号：PSI-5627-0.02mg
产品规格：0.02mg
背景资料：BCAS2 Antibody: BCAS2 was identified through differential display analysis as an mRNA species that was overexpressed in MCF7 and BT-20 breast cancer cell lines. The chromosomal region containing this gene, 1p13.3021, is amplified in these cells lines. BCAS2 is a transcriptional cofactor that enhances estrogen receptor-mediated gene expression, and directly interacts with the tumor suppressor p53 to reduce p53 transcriptional activity by reducing p53 protein level in the absence of DNA damage. Deprivation of BCAS2 through RNA inhibition induces apoptosis in p53-wild type cells, but causes G2-M arrest in p53-null or -mutant cells; this effect was reversed with the expression of ectopic BCAS2. BCAS2 may thus be potentially useful as a therapeutic target in the treatment of cancer.
保存建议：BCAS2 抗体-BCAS2 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型：E, WB, IHC-P, IF
点击：BCAS2 抗体-BCAS2 Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品中心。
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文献和实验
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