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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
PRDM16 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human PRDM16.<br>The immunogen is located within amino acids 1120 - 1170 of PRDM16.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB, IHC-P, IF
- 抗体英文名:
PRDM16 Antibody
- 抗体名:
PRDM16 Antibody
- 规格:
0.02mg
PRDM16 抗体,PRDM16 Antibody,PRDM16 抗体,PRDM16 Antibody
产品名称:PRDM16 抗体-PRDM16 Antibody
产品货号:PSI-5555-0.02mg
产品规格:0.02mg
背景资料:PRDM16 Antibody: PRDM16 is a zinc finger transcription factor and contains an N-terminal PR domain. The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36, q21)-positive MDS/AML. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Recent studies have shown that PRDM16 normally acts as a Smad3 binding protein that may be important for the development of orofacial structures through modulation of the TGF-beta signaling pathway. Other experiments have indicated that PRDM16 controls a bidirectional cell fate switch between skeletal myoblasts and brown fat cells.
保存建议:PRDM16 抗体-PRDM16 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB, IHC-P, IF
点击:PRDM16 抗体-PRDM16 Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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