TMEM38A 抗体-TMEM38A Antibody

TMEM38A 抗体，TMEM38A Antibody，TMEM38A 抗体,TMEM38A Antibody

产品名称：TMEM38A 抗体-TMEM38A Antibody

产品货号：PSI-5521-0.02mg

产品规格：0.02mg

背景资料：TMEM38A Antibody: TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain and localizes to the sarcoplasmic reticulum (SR) in muscle tissues. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure; the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.

保存建议：TMEM38A 抗体-TMEM38A Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, IF

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