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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
IDH1 antibody was raised against a 13 amino acid synthetic peptide near the carboxy terminus of human IDH1.<br>The immunogen is located within the last 50 amino acids of IDH1.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
兔
- 应用范围:
E, WB
- 抗体英文名:
IDH1 Antibody
- 抗体名:
IDH1 Antibody
- 规格:
0.02mg
IDH1 抗体,IDH1 Antibody,IDH1 抗体,IDH1 Antibody
产品名称:IDH1 抗体-IDH1 Antibody
产品货号:PSI-5819-0.02mg
产品规格:0.02mg
背景资料:IDH1 Antibody: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Two NADP(+)-dependent isocitrate dehydrogenases have been found as homodimer: IDH1 is predominantly cytosolic and peroxisomal and IDH2 is mitochondrial. The presence of IDH1 in peroxisomes suggests it may play a role in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic IDH1 serves a significant role in cytoplasmic NADPH production. Defects in IDH1 are involved in the development of glioma.
保存建议:IDH1 抗体-IDH1 Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB
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