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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
C-raf antibody was raised against an 19 amino acid synthetic peptide near the amino terminus of human C-raf.<br>The immunogen is located within amino acids 30 - 80 of C-raf.
- 保存条件:
stored at 4℃ for three months and -20℃, stable for up to one year
- 保质期:
1年
- 级别:
科研级别
- 库存:
100
- 供应商:
艾美捷科技
- 宿主:
鸡
- 应用范围:
E, WB
- 抗体英文名:
C-raf Antibody
- 抗体名:
C-raf Antibody
- 规格:
0.02mg
C-raf 抗体,C-raf Antibody,C-raf 抗体,C-raf Antibody
产品名称:C-raf 抗体-C-raf Antibody
产品货号:PSI-5779-0.02mg
产品规格:0.02mg
背景资料:C-raf Antibody: C-raf is the cellular homolog of viral raf gene (v-raf) and encodes a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases. Once activated, C-raf phosphorylates and activates the protein kinases MEK1 and MEK2, which in turn phosphorylate and activate the serine/threonine specific protein kinases, ERK1 and ERK2. These activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2.
保存建议:C-raf 抗体-C-raf Antibody stored at 4℃ for three months and -20℃, stable for up to one year
应用类型:E, WB
点击:C-raf 抗体-C-raf Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请垂询艾美捷科技有限公司。更多ProSci公司特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品中心。
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文献和实验The progress made in understanding the molecular basis of mammalian cell transformation has led to the unifying concept of growth regulation and its disorders in cancer cells. Today it is well recognized that many products of “cancer genes
Raf/MEK/MAPK Signaling Stimulates the Nuclear Translocation and Transactivating Activity of FOXM1
at late-G1 and S phases. Nuclear translocation occurs just before progression into the G2/M phase of the cell cycle and requires activity of the Raf/MEK/MAPK signaling pathway. Using pharmacological modulators, we demonstrated that activity of the Raf/MEK
Generation of Antibody Molecules Through Antibody Engineering
Twenty-five years ago, Georges K�hler and C�sar Milstein invented a means of cloning individual antibodies, thus opening up the way for tremendous advances in the fields of cell biology and clinical diagnostics ( 1 ). However, in spite
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