TNFAIP3 抗体-TNFAIP3 Antibody

TNFAIP3 抗体，TNFAIP3 Antibody，TNFAIP3 抗体,TNFAIP3 Antibody

产品名称：TNFAIP3 抗体-TNFAIP3 Antibody

产品货号：PSI-5131-0.02mg

产品规格：0.02mg

背景资料：TNFAIP3 Antibody: TNFAIP3, also known as A20, is located in chromosome band 6q23, a region that is often deleted in B cell lymphomas. Recently, it was identified as a tumor suppressor gene in Hodgkin lymphoma and several subtypes of non-Hodgkin lymphomas. TNFAIP3 was initially identified as a zinc-finger protein that is rapidly and transiently induced by TNF-α, inhibiting NF-κB-dependent gene expression, and protecting cells from TNF-α-cytotoxicity. Overexpression of TNFAIP3 also inhibits the TLR2- and TLR4-mediated interleukin-8 synthesis in airway epithelial cells, suggesting that TNFAIP3 also acts as a negative regulator of TLR-mediated inflammatory responses, thereby protecting the host against harmful over-responses to pathogens. At least two isoforms of TNFAIP3 are known to exist.

保存建议：TNFAIP3 抗体-TNFAIP3 Antibody stored at 4℃ for three months and -20℃, stable for up to one year

应用类型：E, WB, IHC-P, IF

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